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It can be used as an organic solvent, reaction medium, and intermediate of organic synthesis. It is widely used. It has high selective extraction ability and is used as solvent for polymerization and condensation of acrylic resin and polysulfone ester, solvent for polymerization and extraction of polyacrylonitrile and acetic acid fiber, extraction solvent for separation of alkane and aromatic hydrocarbons, extraction of aromatic hydrocarbons and butadiene, spinning of acrylic, solvent for plastics and reaction medium for organic synthesis of dyes, pharmaceuticals and other industries.

In medicine, dimethyl sulfoxide has anti-inflammatory and pain-relieving effects. It has strong permeability to the skin, so it can dissolve to dissolve certain drugs so that such drugs can penetrate the body for therapeutic purposes. This carrier property of dimethyl sulfoxide can also be used as an additive for pesticides. Adding small amounts of dimethyl sulfoxide to certain pesticides helps the pesticide penetrate the plant to improve its efficacy.