MF：C17H25N3O5S?3H2O

MW：437.51

Description：Almost white to light yellow crystalline power.

Identification：

IR:comparable IR spectra with standard spectra

UV: UV absorption spectrum of sample solution and standard solution should exhibit maima and minima at same wavelengh

Water content(By KF)：

Between 11.4%w/w and 13.4%w/w

Specific optical rotation：-17° to -21°(at 20℃ ,OAB 0.22g/water 50ml, 100mm)

Heavy metals：Not more than 0.001%(10ppm)

Residue on ignition：Nor more than 0.1%w/w

Assay (By HPLC)：NLT 98.0%w/w(OAB)

Bacterial endotoxins：NMT 0.125 USP EU/mg

Abstract:Meropenem which was synthesized in 1990 for the first time is the first 1β-methyl carbapenem antibiotic. It is stable to β-lactamases and renal dehydropeptidase-Ⅰ(DHP-Ⅰ),and can be used for mono-therapy and not necessary to be combined with dehydropeptidase inhibitors.